As a technical board member I would be against trying to move the admin to any JS framework. Django has outlasted (the peak popularity of) many “cutting edge” JS frameworks, so we cannot bet on any of them continuing to exist and be maintained.
And indeed as Ken noted, the admin is not for developing your “core application” in. You’re free to use Vue, htmx, Alpine or whatever you feel like for your own admin extensions. But we wouldn’t want them in core, dependend on by Django’s wide userbase.